Name | ketotifen fumarate |
Synonyms | Alaway zaditor Zaditen zaditen Zaditor Allerkif Anatifen UNII-HBD503WORO HC 20,511 fumarate ketotifen fumarate Ketotifene fumarate KETOTIFEN FUMARATE EP Ketotifen hydrogen fumarate 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one 1-methyl-4-(10-oxo-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)piperidinium 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate 4,9-Dihydro-4-(1-methylpiperidin-4-ylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophene-10-one fumarate 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (2E)-but-2-enedioate |
CAS | 34580-14-8 |
EINECS | 252-100-0 |
InChI | InChI=1/C19H19NOS.C4H4O4/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19;5-3(6)1-2-4(7)8/h2-5,8,11H,6-7,9-10,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+ |
InChIKey | YNQQEYBLVYAWNX-WLHGVMLRSA-N |
Molecular Formula | C23H23NO5S |
Molar Mass | 425.5 |
Melting Point | 192 C |
Boling Point | 488.9°C at 760 mmHg |
Flash Point | 249.5°C |
Water Solubility | Soluble in water (10 mg/ml), DMSO (100 mM), and methanol. |
Solubility | Slightly soluble in water and ethanol, easily soluble in methanol, slightly soluble in chloroform and acetone. |
Vapor Presure | 1.05E-09mmHg at 25°C |
Appearance | White solid |
Color | White to Pale Beige |
Maximum wavelength(λmax) | ['297nm(MeOH)(lit.)'] |
Merck | 14,5307 |
PH | pH (10g/l, 25℃) : 3.0~4.0 |
Storage Condition | 2-8°C |
MDL | MFCD00079394 |
Physical and Chemical Properties | This product is a white (or yellowish) crystalline powder, odorless, bitter, slightly soluble in water and ethanol, very soluble in methanol, very slightly soluble in chloroform and acetone. |
Use | Antihistamines, Antiasthmatic drugs, for the prevention and treatment of bronchitis asthma |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
Safety Description | S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
RTECS | DE8260000 |
HS Code | 29349990 |
Reference Show more | 1. [IF=6.53] Ziye Huang et al."Mechanism of ketotifen fumarate inhibiting renal calcium oxalate stone formation in SD rats."BIOMEDICINE & PHARMACOTHERAPY. 2022 Jul;151:113147 |